The CRM 2011 Rollup 1 will be part of Windows Update on April,26th, so take extra steps if you don't want it installed. At the time of writing, no major bugs have been found in UR1, while a lot are fixed, so it may also be a good time to upgrade.
When connecting CRM 2011 online, if you get the exception Unhandled Exception: "System.ServiceModel.Security.MessageSecurityException: An unsecured or incorrectly secured fault was received from the other party", here's the solution.
If you are concerned about the security of your data in the public cloud, here's an interesting article about the UK Police using a private cloud for deploying Microsoft CRM.
By the way, Travi@ta has teamed with Belgacom to offer secure Microsoft CRM private clouds solutions in Belgium, you can find more information on http://www.belgacom.be/crm or direct contact info here.